Title : HIV Nef-mediated CD4 down-regulation is adaptor protein complex 2 dependent.

Pub. Date : 2005 Sep 1

PMID : 16116206






2 Functional Relationships(s)
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1 However, the mechanistic connection between the C-terminal dileucine motif of Nef and the component(s) of the clathrin-coated pits has not been pinpointed. dileucine S100 calcium binding protein B Homo sapiens
2 The results demonstrate that, like the tyrosine sorting motif-dependent endocytosis (for which the transferrin receptor and the epidermal growth factor receptor are the two prototypes), dileucine sorting motif-dependent endocytosis of Nef and CD4 are also AP-2 dependent. dileucine S100 calcium binding protein B Homo sapiens