Title : Lipids as modulators of proteolytic activity of BACE: involvement of cholesterol, glycosphingolipids, and anionic phospholipids in vitro.

Pub. Date : 2005 Nov 4

PMID : 16115865






2 Functional Relationships(s)
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1 Lipids as modulators of proteolytic activity of BACE: involvement of cholesterol, glycosphingolipids, and anionic phospholipids in vitro. Cholesterol beta-secretase 1 Homo sapiens
2 We have identified 3 groups of lipids that stimulate proteolytic activity of BACE: 1) neutral glycosphingolipids (cerebrosides), 2) anionic glycerophospholipids, and 3) sterols (cholesterol). Cholesterol beta-secretase 1 Homo sapiens