Pub. Date : 2004 Dec
PMID : 16114557
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | [Effect of EGCG on H2O2-induced MnSOD gene expression in cultured spiral ganglion cells]. | epigallocatechin gallate | superoxide dismutase 2 | Homo sapiens |
| 2 | OBJECTIVE: To investigate the influence of EGCG on H2O2-induced gene expression of manganese superoxide dismutase (MnSOD or SOD2) in cultured spiral ganglion cells (SGCs) in vitro. | epigallocatechin gallate | superoxide dismutase 2 | Homo sapiens |
| 3 | Semi-quantitative RT-PCR was applied to observe MnSOD gene expression in SGCs after H2O2 and EGCG treatment. | epigallocatechin gallate | superoxide dismutase 2 | Homo sapiens |
| 4 | CONCLUSION: EGCG suppresses H2O2-induced up-regulation of MnSOD gene expression in cultured SGCs by getting rid of oxygen free radicals, reinforcing the activity of antioxidant enzymes such as MnSOD, and protects cultured SGCs from H2O2-induced oxidizing damage. | epigallocatechin gallate | superoxide dismutase 2 | Homo sapiens |
| 5 | CONCLUSION: EGCG suppresses H2O2-induced up-regulation of MnSOD gene expression in cultured SGCs by getting rid of oxygen free radicals, reinforcing the activity of antioxidant enzymes such as MnSOD, and protects cultured SGCs from H2O2-induced oxidizing damage. | epigallocatechin gallate | superoxide dismutase 2 | Homo sapiens |