Title : Elevated ERK1/ERK2/estrogen receptor cross-talk enhances estrogen-mediated signaling during long-term estrogen deprivation.

Pub. Date : 2005 Jul

PMID : 16113101






1 Functional Relationships(s)
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1 We have shown that long-term culture of MCF7 cells in medium depleted of oestrogen (LTED) results in hypersensitivity to oestradiol (E2) coinciding with elevated levels of both ERalpha phosphorylated on Ser(118) and ERK1/ERK2. Estradiol mitogen-activated protein kinase 3 Homo sapiens