Pub. Date : 2005 Sep
PMID : 16108864
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Metformin reduces C-reactive protein but not complement factor C3 in overweight patients with Type 2 diabetes mellitus. | Metformin | C-reactive protein | Homo sapiens |
| 2 | AIMS: To determine the influence of metformin treatment on plasma C-reactive protein (CRP) and complement factor C3. | Metformin | C-reactive protein | Homo sapiens |
| 3 | AIMS: To determine the influence of metformin treatment on plasma C-reactive protein (CRP) and complement factor C3. | Metformin | C-reactive protein | Homo sapiens |
| 4 | The difference in ratios of CRP levels at each visit to baseline between placebo- (n = 16) and metformin-treated (n = 26) subjects was significantly different at the 12-week (P = 0.002) and 24-week (P = 0.03) visits. | Metformin | C-reactive protein | Homo sapiens |
| 5 | CONCLUSION: Metformin may have a specific interaction with mechanisms involved in CRP synthesis or secretion, not directly related to improved insulin sensitivity and dampening of chronic inflammation. | Metformin | C-reactive protein | Homo sapiens |