Pub. Date : 2005
PMID : 16103732
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In this study, using in vitro and in vivo models, we examined the effects of cyclosporine (CsA) and tacrolimus (TAC) on OPN mRNA and protein expression. | Cyclosporine | secreted phosphoprotein 1 | Mus musculus |
| 2 | In this study, using in vitro and in vivo models, we examined the effects of cyclosporine (CsA) and tacrolimus (TAC) on OPN mRNA and protein expression. | Cyclosporine | secreted phosphoprotein 1 | Mus musculus |
| 3 | We also examined if CsA- and TAC-induced OPN expression is dependent on transforming growth factor (TGF)-beta expression. | Cyclosporine | secreted phosphoprotein 1 | Mus musculus |
| 4 | The expression of OPN was also studied in CsA-treated PTE cells with and without anti-TGF-beta antibody. | Cyclosporine | secreted phosphoprotein 1 | Mus musculus |
| 5 | OPN may contribute to the CsA- and TAC-induced nephrotoxicity in organ transplant recipients and the increased OPN expression might be mediated by TGF-beta. | Cyclosporine | secreted phosphoprotein 1 | Mus musculus |