Title : Functional characterisation of the S512Y mutant vanilloid human TRPV1 receptor.

Pub. Date : 2005 Nov

PMID : 16100528






1 Functional Relationships(s)
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1 2 In this study, switching the equivalent residue in the human TRPV1 (which has some significant differences with the rat TRPV1) also rendered this channel relatively insensitive to activation by capsaicin and proved critical in determining the receptor"s sensitivity to the putative endovanilloid N-arachidonoyl-dopamine (NADA), suggesting a similar mode of activation for these two agonists. Capsaicin transient receptor potential cation channel subfamily V member 1 Homo sapiens