Title : The inhibitory effect of alendronate, a nitrogen-containing bisphosphonate on the PI3K-Akt-NFkappaB pathway in osteosarcoma cells.

Pub. Date : 2005 Nov

PMID : 16100524






1 Functional Relationships(s)
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1 The aim of the present study was to determine the effect of alendronate, one of the nitrogen-containing bisphosphonates on the phoshoinositide 3-kinase (PI3K)-Akt-NFkappaB pathway, the major cell survival pathway. Diphosphonates nuclear factor kappa B subunit 1 Homo sapiens