Title : N-methyl-N-nitrosourea-induced apoptosis of photoreceptor cells in Sprague-Dawley rats via nuclear factor-kappaB.

Pub. Date : 2005 Jul 5

PMID : 16098260






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 In apoptotic cascade, the protein levels of NF-kappaB p65 were only detected after MNU treatment for 12 and 24 hours in the nucleus. Methylnitrosourea synaptotagmin 1 Rattus norvegicus
2 CONCLUSIONS: MNU-induced photoreceptor cell destruction was attributed to the apoptotic process by down-regulating the activation of NF-kappaB p65. Methylnitrosourea synaptotagmin 1 Rattus norvegicus