Title : Stereoselective route to the ezoaminuroic acid core of the ezomycins.

Pub. Date : 2005 Aug 19

PMID : 16095320






1 Functional Relationships(s)
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1 A key transformation in the synthesis involves regio- and stereoselective conversion of the olefinic functionality of a 5,6-dihydropyran-2-one to the C-2, C-3 trans-1,2-amino alcohol moiety as present in ezoaminuroic acid. Alcohols complement C3 Homo sapiens