Pub. Date : 2005
PMID : 16095054
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Urinary excretion of aquaporin-2 after furosemide and felodipine in healthy humans. | Furosemide | aquaporin 2 | Homo sapiens |
| 2 | We sought to test the hypotheses that urinary excretion of aquaporin-2 (U-AQP2) increases after a single intravenous dose of furosemide, and that U-AQP2 decreases after a single oral dose of felodipine. | Furosemide | aquaporin 2 | Homo sapiens |
| 3 | We sought to test the hypotheses that urinary excretion of aquaporin-2 (U-AQP2) increases after a single intravenous dose of furosemide, and that U-AQP2 decreases after a single oral dose of felodipine. | Furosemide | aquaporin 2 | Homo sapiens |
| 4 | RESULTS: Furosemide treatment increased U-AQP2 (202%), urine volume (214%), and FENa by a factor of 11, (p < 0.001 for all), whereas CH2O and GFR were unchanged. | Furosemide | aquaporin 2 | Homo sapiens |
| 5 | CONCLUSIONS: Furosemide treatment increased U-AQP2, AVP, and the activity of the renin-angiotensin-aldosterone system. | Furosemide | aquaporin 2 | Homo sapiens |