Title : Control of ASPP2/(53BP2L) protein levels by proteasomal degradation modulates p53 apoptotic function.

Pub. Date : 2005 Oct 14

PMID : 16091363






1 Functional Relationships(s)
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1 More importantly, small interfering RNA knockdown of ASPP2/(53BP2L) levels attenuated bortezomib-induced apoptosis, and this effect was greater in wild-type p53 cells. Bortezomib tumor protein p53 Homo sapiens