Title : Identification and characterization of a response element in the EGFR promoter that mediates transcriptional repression by 1,25-dihydroxyvitamin D3 in breast cancer cells.

Pub. Date : 2005 Aug

PMID : 16087726






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 In the present report, functional mapping of the EGFR promoter in BT549 cells has revealed a sequence of DNA between nucleotide positions -536 and -478 that resembles a consensus vitamin D response element (VDRE) and confers a vitamin D response upon both the homologous and a minimal heterologous promoter. Vitamin D epidermal growth factor receptor Homo sapiens
2 In the present report, functional mapping of the EGFR promoter in BT549 cells has revealed a sequence of DNA between nucleotide positions -536 and -478 that resembles a consensus vitamin D response element (VDRE) and confers a vitamin D response upon both the homologous and a minimal heterologous promoter. Vitamin D epidermal growth factor receptor Homo sapiens