Title : Update on cyclooxygenase inhibitors: has a third COX isoform entered the fray?

Pub. Date : 2005 Aug

PMID : 16083531






1 Functional Relationships(s)
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1 Highly selective COX-2 inhibitors including celecoxib, rofecoxib, valdecoxib, lumiracoxib, and etoricoxib were developed with the hope of significantly reducing the serious gastrointestinal toxicities associated with chronic high-dose NSAID use. rofecoxib mitochondrially encoded cytochrome c oxidase II Homo sapiens