Title : SIRPbeta1 is expressed as a disulfide-linked homodimer in leukocytes and positively regulates neutrophil transepithelial migration.

Pub. Date : 2005 Oct 28

PMID : 16081415






2 Functional Relationships(s)
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1 SIRPbeta1 is expressed as a disulfide-linked homodimer in leukocytes and positively regulates neutrophil transepithelial migration. Disulfides superoxide dismutase 1 Homo sapiens
2 Furthermore, although SIRPalpha (Bit/PTPNS-1) is expressed as a monomer, we showed that SIRPbeta1 is expressed on the cell surface as a disulfide-linked homodimer with bond formation mediated by Cys-320 in the membrane-proximal Ig loop. Disulfides superoxide dismutase 1 Homo sapiens