Title : Spontaneous homologous recombination is induced by collapsed replication forks that are caused by endogenous DNA single-strand breaks.

Pub. Date : 2005 Aug

PMID : 16055725






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 An SSB repair-defective cell line, EM9 with an XRCC1 mutation, has an increased number of spontaneous gammaH2Ax and RAD51 foci, suggesting that endogenous SSBs collapse replication forks, triggering recombination repair. ssbs X-ray repair cross complementing 1 Homo sapiens