Title : c-Jun N-terminal kinase activation in dorsal root ganglion contributes to pain hypersensitivity.

Pub. Date : 2005 Sep 16

PMID : 16055088






1 Functional Relationships(s)
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1 Pre-treatment as well as post-treatment of rats with a JNK inhibitor, SP600125, significantly attenuated thermal hyperalgesia, as assessed by paw-withdrawal latency, and the upregulation of c-fos immunoreactivity in dorsal horn neurons. pyrazolanthrone Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus