Pub. Date : 2006 Jan
PMID : 16054375
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Simvastatin reduces caspase-3 activation and inflammatory markers induced by hypoxia-ischemia in the newborn rat. | Simvastatin | caspase 3 | Rattus norvegicus |
| 2 | In simvastatin-treated ischemic animals, the expression of these proteins and caspase-3 activity were significantly lower when compared to that of ischemic animals. | Simvastatin | caspase 3 | Rattus norvegicus |
| 3 | The results indicate that simvastatin-induced attenuation of hypoxia-ischemia brain injury in the newborn rat occurs through reduction of the inflammatory response, caspase-3 activation, and apoptotic cell death. | Simvastatin | caspase 3 | Rattus norvegicus |