Title : Disposition of formononetin via enteric recycling: metabolism and excretion in mouse intestinal perfusion and Caco-2 cell models.

Pub. Date : 2005 Jul-Aug

PMID : 16053335






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Multidrug-resistance-related protein (MRP) inhibitors (leukotriene C(4) plus MK-571, C(26)H(26)ClN(2)O(3)S(2)) significantly decreased the excretion of glucuronide and sulfate in mouse intestine (52-74% for glucuronide, 13-26% for sulfate) and in Caco-2 cells (92% for glucuronide, 37% for sulfate). Leukotriene C4 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 Mus musculus
2 Multidrug-resistance-related protein (MRP) inhibitors (leukotriene C(4) plus MK-571, C(26)H(26)ClN(2)O(3)S(2)) significantly decreased the excretion of glucuronide and sulfate in mouse intestine (52-74% for glucuronide, 13-26% for sulfate) and in Caco-2 cells (92% for glucuronide, 37% for sulfate). Leukotriene C4 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 Mus musculus