Title : Pharmacogenetic study of apolipoprotein E, cholesteryl ester transfer protein and hepatic lipase genes and simvastatin therapy in Brazilian subjects.

Pub. Date : 2005 Dec

PMID : 16038892






1 Functional Relationships(s)
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1 CONCLUSION: Our study demonstrates that individual plasma HDL-cholesterol response to simvastatin is mediated, in part, by the CETP gene locus, with the B2 homozygotes having more benefit in HDL-C improvement than carriers of B1 allele. Simvastatin cholesteryl ester transfer protein Homo sapiens