Pub. Date : 2005 Jul 15
PMID : 16033851
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | RESULTS: Treatment of MCF7/Aro cells with estradiol or androstenedione caused modulation of the mTOR pathway, a phenomenon reversed by letrozole or RAD001. | Androstenedione | cytochrome P450 family 19 subfamily A member 1 | Homo sapiens |
| 2 | In MCF7/Aro and T47D/Aro cells, both agents inhibited androstenedione-induced proliferation; however, in combination, this was significantly augmented (P < 0.001, two-way ANOVA, synergy by isobologram analysis). | Androstenedione | cytochrome P450 family 19 subfamily A member 1 | Homo sapiens |
| 3 | In MCF7/Aro and T47D/Aro cells, both agents inhibited androstenedione-induced proliferation; however, in combination, this was significantly augmented (P < 0.001, two-way ANOVA, synergy by isobologram analysis). | Androstenedione | cytochrome P450 family 19 subfamily A member 1 | Homo sapiens |