Title : Sequential conformation changes of chinese hamster ovary dihydrofolate reductase at its active sites.

Pub. Date : 2005 Jul

PMID : 16029162






1 Functional Relationships(s)
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1 The local fluorescence probes, 2-(p-toluidino)-6-naphthalenesulfonic acid (TNS) and NADPH were employed to detect urea-induced conformation changes at each active site of dihydrofolate reductase (DHFR), respectively. NADP dihydrofolate reductase Cricetulus griseus