Title : Autocrine vascular endothelial growth factor/vascular endothelial growth factor receptor-2 growth pathway represents a cyclooxygenase-2-independent target for the cyclooxygenase-2 inhibitor NS-398 in colon cancer cells.

Pub. Date : 2005

PMID : 16015035






3 Functional Relationships(s)
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Protein Name
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1 Autocrine vascular endothelial growth factor/vascular endothelial growth factor receptor-2 growth pathway represents a cyclooxygenase-2-independent target for the cyclooxygenase-2 inhibitor NS-398 in colon cancer cells. N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide vascular endothelial growth factor A Homo sapiens
2 Autocrine vascular endothelial growth factor/vascular endothelial growth factor receptor-2 growth pathway represents a cyclooxygenase-2-independent target for the cyclooxygenase-2 inhibitor NS-398 in colon cancer cells. N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide vascular endothelial growth factor A Homo sapiens
3 CONCLUSION: The autocrine VEGF/VEGFR-2 growth pathway could be a COX-2-independent target of the COX-2 inhibitor, NS-398, in colon cancer cells. N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide vascular endothelial growth factor A Homo sapiens