Title : Effects of nicotine on proliferation, cell cycle, and differentiation in immortalized and malignant oral keratinocytes.

Pub. Date : 2005 Aug

PMID : 16011614






1 Functional Relationships(s)
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1 Nicotine treatment increased p21 expression in immortalized cells (HaCaT, IHOK) and oral cancer cells (HN4, HN12), but decreased pRb and p53 expression in oral cancer cells. Nicotine tumor protein p53 Homo sapiens