Pub. Date : 2005 Aug
PMID : 16010437
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | ATO activated the intrinsic (mitochondrial) pathway of apoptosis, which involved disrupting mitochondrial membrane potential, increased Bax/Bcl-2 ratio and caspase-9 activation, as well as the extrinsic (death receptor) pathway mediated by Fas and caspase-8 activation. | Arsenic Trioxide | BCL2 associated X, apoptosis regulator | Homo sapiens |