Title : SK-7041, a new histone deacetylase inhibitor, induces G2-M cell cycle arrest and apoptosis in pancreatic cancer cell lines.

Pub. Date : 2006 Jun 8

PMID : 16009488






2 Functional Relationships(s)
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Protein Name
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1 The expression levels of Mcl-1 and Bcl-XL but not those of Bcl-2, Bax, and Bak were suppressed by TSA or SK-7041 treatment. trichostatin A BCL2 like 1 Homo sapiens
2 SK-7041 or TSA induced apoptosis and G2-M cell cycle arrest by up-regulating p21 and down-regulating cyclin B1, Mcl-1, and Bcl-XL. trichostatin A BCL2 like 1 Homo sapiens