Pub. Date : 1992 Jun 1
PMID : 1599423
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | High levels of thermogenin could be induced by noradrenaline treatment in cells grown for more than 5 days in culture, and in such cell cultures continuously stimulated with noradrenaline, the thermogenin level continued to increase for at least a further 5 days. | Norepinephrine | uncoupling protein 1 (mitochondrial, proton carrier) | Mus musculus |
| 2 | High levels of thermogenin could be induced by noradrenaline treatment in cells grown for more than 5 days in culture, and in such cell cultures continuously stimulated with noradrenaline, the thermogenin level continued to increase for at least a further 5 days. | Norepinephrine | uncoupling protein 1 (mitochondrial, proton carrier) | Mus musculus |
| 3 | In cell cultures continuously stimulated with noradrenaline for 5 days, the induced thermogenin was degraded much more slowly after noradrenaline removal, with a half-life of 70 h. This half-life was unchanged by cycloheximide treatment, and the degradation after cycloheximide was in parallel with the degradation of protein in general, and was therefore non-specific. | Norepinephrine | uncoupling protein 1 (mitochondrial, proton carrier) | Mus musculus |
| 4 | In cell cultures continuously stimulated with noradrenaline for 5 days, the induced thermogenin was degraded much more slowly after noradrenaline removal, with a half-life of 70 h. This half-life was unchanged by cycloheximide treatment, and the degradation after cycloheximide was in parallel with the degradation of protein in general, and was therefore non-specific. | Norepinephrine | uncoupling protein 1 (mitochondrial, proton carrier) | Mus musculus |