Pub. Date : 2006 Feb 1
PMID : 15990133
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We investigated the hepatic expression of CYP1 and AhR following oral administration of DMBA (100 mg/kg b.w.) | 6,11-dimethylbenzo(b)naphtho(2,3-d)thiophene | cytochrome P450, family 1, subfamily b, polypeptide 1 | Rattus norvegicus |
| 2 | Because DMBA oxidation produces a highly mutagenic metabolite and is finally catalyzed by CYP1B1, a relatively low PCB126 dose might produce the biological character to potentially increase the risk of DMBA-induced mammary carcinoma. | 6,11-dimethylbenzo(b)naphtho(2,3-d)thiophene | cytochrome P450, family 1, subfamily b, polypeptide 1 | Rattus norvegicus |
| 3 | Because DMBA oxidation produces a highly mutagenic metabolite and is finally catalyzed by CYP1B1, a relatively low PCB126 dose might produce the biological character to potentially increase the risk of DMBA-induced mammary carcinoma. | 6,11-dimethylbenzo(b)naphtho(2,3-d)thiophene | cytochrome P450, family 1, subfamily b, polypeptide 1 | Rattus norvegicus |