Title : Cells with pathogenic biallelic mutations in the human MUTYH gene are defective in DNA damage binding and repair.

Pub. Date : 2005 Nov

PMID : 15987719






1 Functional Relationships(s)
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Protein Name
Organism
1 Mutant MUTYH proteins in these four cell lines possess significantly lowered binding and cleavage activities with heteroduplex oligonucleotides containing A.8-oxoG and 8-oxoA.G mispairs. Oligonucleotides mutY DNA glycosylase Homo sapiens