Title : Wild-type alpha-synuclein interacts with pro-apoptotic proteins PKCdelta and BAD to protect dopaminergic neuronal cells against MPP+-induced apoptotic cell death.

Pub. Date : 2005 Sep 13

PMID : 15978696






1 Functional Relationships(s)
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1 Recently, we demonstrated that 1-methyl-4-phenylpyridinium (MPP+) induces caspase-3-dependent proteolytic activation of PKCdelta, which subsequently contributes to neuronal apoptotic cell death in mesencephalic dopaminergic neuronal cells. 1-Methyl-4-phenylpyridinium caspase 3 Homo sapiens