Title : Antiproliferative activity of melatonin by transcriptional inhibition of cyclin D1 expression: a molecular basis for melatonin-induced oncostatic effects.

Pub. Date : 2005 Aug

PMID : 15978052






1 Functional Relationships(s)
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1 Reporter gene assays indicate that the same portion of the cyclin D1 promoter which confers estrogen sensitivity, encompassing a potential cAMP responsive element binding site, is repressed by melatonin. Cyclic AMP cyclin D1 Homo sapiens