Title : Inhibitory effects of 12-O-tetradecanoylphorbol-13-acetate alone or in combination with all-trans retinoic acid on the growth of cultured human pancreas cancer cells and pancreas tumor xenografts in immunodeficient mice.

Pub. Date : 2005 Oct

PMID : 15976015






2 Functional Relationships(s)
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1 Inhibition of proliferation by TPA in PANC-1 cells was associated with an increase in the level of p21, but this was not observed in MIA PaCa-2 or BxPC-3 cells. Tetradecanoylphorbol Acetate H3 histone pseudogene 16 Homo sapiens
2 The TPA-induced increase of p21 in PANC-1 cells was blocked by bisindolylmaleimide or rottlerin (inhibitors of protein kinase C). Tetradecanoylphorbol Acetate H3 histone pseudogene 16 Homo sapiens