Title : Polyamine depletion inhibits apoptosis following blocking of survival pathways in human chondrocytes stimulated by tumor necrosis factor-alpha.

Pub. Date : 2006 Jan

PMID : 15965903






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Although DFMO increased the amount of active, phosphorylated Akt, inhibitors of the Akt pathway failed to restore the TNF-induced increase in caspase activity blunted by DFMO. Eflornithine AKT serine/threonine kinase 1 Homo sapiens
2 DFMO also reduced the increase in caspase activity induced by staurosporine, but in this case Akt inhibition prevented the DFMO effect. Eflornithine AKT serine/threonine kinase 1 Homo sapiens