Title : Systemic administration of lipopolysaccharide upregulates angiotensin II expression in rat renal tubules: immunohistochemical and ELISA studies.

Pub. Date : 2005 Nov

PMID : 15963602






2 Functional Relationships(s)
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1 When injected at 0.1, 10, or 1000 microg/kg i.p., LPS-induced a dose-related increase in AII-like immunoreactivity in renal tubules that was unaffected by treatment with the prostaglandin-synthesis blocker indomethacin. Prostaglandins angiotensinogen Rattus norvegicus
2 These results suggest that systemically administered LPS induces AII peptide expression in renal tubules by a prostaglandin-independent mechanism. Prostaglandins angiotensinogen Rattus norvegicus