Title : Mefloquine metabolism by human liver microsomes. Effect of other antimalarial drugs.

Pub. Date : 1992 May 8

PMID : 1596283






2 Functional Relationships(s)
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1 The inhibition of ketoconazole, a known inhibitor of cytochrome P450 isozymes, and the dependency of metabolite formation on the presence of NADPH indicated that cytochrome P450 isozyme(s) catalysed metabolite production. NADP cytochrome P450 family 4 subfamily F member 3 Homo sapiens
2 The inhibition of ketoconazole, a known inhibitor of cytochrome P450 isozymes, and the dependency of metabolite formation on the presence of NADPH indicated that cytochrome P450 isozyme(s) catalysed metabolite production. NADP cytochrome P450 family 4 subfamily F member 3 Homo sapiens