Title : CYP2C9 genotype-dependent effects on in vitro drug-drug interactions: switching of benzbromarone effect from inhibition to activation in the CYP2C9.3 variant.

Pub. Date : 2005 Sep

PMID : 15955872






1 Functional Relationships(s)
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1 Although benzbromarone inhibited CYP2C9.1 activity as expected, CYP2C9.3-mediated flurbiprofen 4"-hydroxylation was activated in the presence of benzbromarone. Flurbiprofen cytochrome P450 family 2 subfamily C member 9 Homo sapiens