Title : Gut-derived norepinephrine plays an important role in up-regulating IL-1beta and IL-10.

Pub. Date : 2005 Jun 10

PMID : 15949713






1 Functional Relationships(s)
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1 Since adenylate cyclase activator forskolin prevents the increase in NE-induced IL-1beta and IL-10, the up-regulatory effect of NE on those cytokines appears to be mediated, at least in part, by inhibition of adenylate cyclase and reduction in intracellular cyclic AMP levels. Colforsin interleukin 1 beta Rattus norvegicus