Title : Role of lipid A palmitoylation in bacterial pathogenesis.

Pub. Date : 2005

PMID : 15949146






2 Functional Relationships(s)
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1 The isolation of pagP mutants from pathogenic Gram-negative bacteria has revealed that palmitoylated lipid A can both protect the bacterium from certain host immune defenses and attenuate the ability of lipid A to activate those same defenses through the TLR4 signal transduction pathway. Lipid A toll like receptor 4 Homo sapiens
2 The isolation of pagP mutants from pathogenic Gram-negative bacteria has revealed that palmitoylated lipid A can both protect the bacterium from certain host immune defenses and attenuate the ability of lipid A to activate those same defenses through the TLR4 signal transduction pathway. Lipid A toll like receptor 4 Homo sapiens