Title : Scopoletin induces apoptosis in human promyeloleukemic cells, accompanied by activations of nuclear factor kappaB and caspase-3.

Pub. Date : 2005 Jul 1

PMID : 15936354






1 Functional Relationships(s)
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1 The signal cascade activated by scopoletin included the heterodimeric redox-sensitive transcription factor NF-kappaB, which exhibited an upregulation of nuclear factor-kappa B (NF-kappaB) translocation to the nucleus by increase of IkappaBalpha degradation. Scopoletin NFKB inhibitor alpha Homo sapiens