Title : COX-2 selective nonsteroidal anti-inflammatory drugs: current status.

Pub. Date : 2005 Mar

PMID : 15926604






1 Functional Relationships(s)
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1 COX-2 inhibitors may decrease vascular prostacyclin production and may tip the balance in favour of prothrombotic eicosanoids (thromboxane A2) and lead to increased cardiovascular thrombotic events. Eicosanoids mitochondrially encoded cytochrome c oxidase II Homo sapiens