Title : A rapid new assay to detect RNA editing reveals antipsychotic-induced changes in serotonin-2C transcripts.

Pub. Date : 2005 Sep

PMID : 15917433






2 Functional Relationships(s)
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Protein Name
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1 Whereas haloperidol, a typical antipsychotic drug that is primarily a dopamine receptor antagonist, reduced 5-HT2C VNV isoform frequency and the level of RNA editing at the D site, risperidone and not the prototype atypical antipsychotic drug clozapine increased the frequency of 5-HT2C VNV and D-site editing. Haloperidol 5-hydroxytryptamine receptor 2C Rattus norvegicus
2 Whereas haloperidol, a typical antipsychotic drug that is primarily a dopamine receptor antagonist, reduced 5-HT2C VNV isoform frequency and the level of RNA editing at the D site, risperidone and not the prototype atypical antipsychotic drug clozapine increased the frequency of 5-HT2C VNV and D-site editing. Haloperidol 5-hydroxytryptamine receptor 2C Rattus norvegicus