Title : Functional consequences of single nucleotide polymorphisms in the human organic anion transporter hOAT1 (SLC22A6).

Pub. Date : 2005 Aug

PMID : 15914676






6 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 When expressed in Xenopus oocytes, wild-type R50-hOAT1 and the variants R50H-hOAT1 and K525I-hOAT1 all mediated the probenecid-sensitive uptake of the classic organic anion para-aminohippurate (PAH). p-Aminohippuric Acid solute carrier family 22 member 6 Homo sapiens
2 When expressed in Xenopus oocytes, wild-type R50-hOAT1 and the variants R50H-hOAT1 and K525I-hOAT1 all mediated the probenecid-sensitive uptake of the classic organic anion para-aminohippurate (PAH). p-Aminohippuric Acid solute carrier family 22 member 6 Homo sapiens
3 When expressed in Xenopus oocytes, wild-type R50-hOAT1 and the variants R50H-hOAT1 and K525I-hOAT1 all mediated the probenecid-sensitive uptake of the classic organic anion para-aminohippurate (PAH). p-Aminohippuric Acid solute carrier family 22 member 6 Homo sapiens
4 When expressed in Xenopus oocytes, wild-type R50-hOAT1 and the variants R50H-hOAT1 and K525I-hOAT1 all mediated the probenecid-sensitive uptake of the classic organic anion para-aminohippurate (PAH). p-Aminohippuric Acid solute carrier family 22 member 6 Homo sapiens
5 When expressed in Xenopus oocytes, wild-type R50-hOAT1 and the variants R50H-hOAT1 and K525I-hOAT1 all mediated the probenecid-sensitive uptake of the classic organic anion para-aminohippurate (PAH). p-Aminohippuric Acid solute carrier family 22 member 6 Homo sapiens
6 When expressed in Xenopus oocytes, wild-type R50-hOAT1 and the variants R50H-hOAT1 and K525I-hOAT1 all mediated the probenecid-sensitive uptake of the classic organic anion para-aminohippurate (PAH). p-Aminohippuric Acid solute carrier family 22 member 6 Homo sapiens