Title : Discovery of potent and selective orally bioavailable beta-substituted phenylalanine derived dipeptidyl peptidase IV inhibitors.

Pub. Date : 2005 Jun 15

PMID : 15908206






1 Functional Relationships(s)
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1 anti-Substituted biaryl beta-methylphenylalanine derived amides have been shown to be potent DPP-IV inhibitors that suffer from suboptimal selectivity and pharmacokinetics. Amides dipeptidyl peptidase 4 Homo sapiens