Title : Synergistic activation of JNK/SAPK induced by TNF-alpha and IFN-gamma: apoptosis of pancreatic beta-cells via the p53 and ROS pathway.

Pub. Date : 2005 Dec

PMID : 15908180






1 Functional Relationships(s)
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1 Furthermore, the synergistic effect of TNF-alpha/IFN-gamma on apoptosis and ROS production was further potentiated by the overexpression of wild-type p53, but not with mutant p53. ros tumor protein p53 Homo sapiens