Title : Mitogen-activated protein kinase phosphorylation in the rostral ventrolateral medulla plays a key role in imidazoline (i1)-receptor-mediated hypotension.

Pub. Date : 2005 Sep

PMID : 15901801






2 Functional Relationships(s)
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1 Our previous study showed that rilmenidine, a selective I(1)-imidazoline receptor agonist, enhanced the phosphorylation of mitogen-activated protein kinase (MAPK)(p42/44), via the phosphatidylcholine-specific phospholipase C pathway in the pheochromocytoma cell line (PC12). Rilmenidine mitogen activated protein kinase 3 Rattus norvegicus
2 An increase in RVLM MAPK(p42/44) occurred only after rilmenidine. Rilmenidine mitogen activated protein kinase 3 Rattus norvegicus