Title : Signalling pathway involved in nitric oxide synthase type II activation in chondrocytes: synergistic effect of leptin with interleukin-1.

Pub. Date : 2005

PMID : 15899045






1 Functional Relationships(s)
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1 Pretreatment with tyrphostin AG490 and Tkip (a SOCS-1 mimetic peptide that inhibits JAK2) blocked nitric oxide production induced by leptin/IL-1. Tyrphostins interleukin 1 alpha Homo sapiens