Title : Sexual dimorphism in angiotensin II-induced hypertension and vascular alterations.

Pub. Date : 2005 May

PMID : 15897923






1 Functional Relationships(s)
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1 Chronic treatment with angiotensin II (0.7 mg/kg daily for 10 d) significantly raised arterial blood pressure in male but not female Sprague-Dawley rats; it upregulated the NAD(P)H oxidase gp67 phox subunit in the aorta of male but not female rats; and it exaggerated the vasoconstrictor responses to norepinephrine and serotonin in the mesenteric vascular bed (MVB) of male but not female rats. Norepinephrine angiotensinogen Rattus norvegicus