Pub. Date : 2005 Feb
PMID : 15895830
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The ERK activation and cell death induced by H2O2 was prevented by catalase, the hydrogen peroxide scavenger, and U0126, an inhibitor of ERK upstream kinase MEK1/2. | Hydrogen Peroxide | mitogen-activated protein kinase kinase 1 | Homo sapiens |
| 2 | Transient transfection with constitutive active MEK1, an upstream activator of ERK1/2, increased H2O2-induced cell death, whereas transfection with dominant-negative mutants of MEK1 decreased the cell death. | Hydrogen Peroxide | mitogen-activated protein kinase kinase 1 | Homo sapiens |
| 3 | Transient transfection with constitutive active MEK1, an upstream activator of ERK1/2, increased H2O2-induced cell death, whereas transfection with dominant-negative mutants of MEK1 decreased the cell death. | Hydrogen Peroxide | mitogen-activated protein kinase kinase 1 | Homo sapiens |