Title : Neuroprotection by hypoxic preconditioning involves oxidative stress-mediated expression of hypoxia-inducible factor and erythropoietin.

Pub. Date : 2005 Jun

PMID : 15890996






1 Functional Relationships(s)
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1 CONCLUSIONS: Hypoxic preconditioning induces ROS, which may downregulate the threshold for production of HIF-1alpha and Epo expression during subsequent lethal hypoxia, thus exerting neuroprotection through the Jak2-Stat5 and NF-kappaB pathways. Reactive Oxygen Species erythropoietin Mus musculus