Pub. Date : 2005 Jun
PMID : 15870934
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | p21Waf1/Cip1 is a common target induced by short-chain fatty acid HDAC inhibitors (valproic acid, tributyrin and sodium butyrate) in neuroblastoma cells. | Valproic Acid | cyclin dependent kinase inhibitor 1A | Homo sapiens |
| 2 | Moreover, we addressed the question of whether the cyclin-dependent kinase inhibitors p21(Cip1) and p27(Kip1) are involved in the mechanism of action of members of the short-chain fatty acids class (VPA, sodium butyrate and tributyrin) of HDAC inhibitors, in human NB cells. | Valproic Acid | cyclin dependent kinase inhibitor 1A | Homo sapiens |
| 3 | These results suggest that p21(Cip1) could be involved in the inhibition of proliferation and induction of differentiation in human NB cells induced by treatment with VPA or tributyrin or sodium butyrate. | Valproic Acid | cyclin dependent kinase inhibitor 1A | Homo sapiens |
| 4 | These results suggest that p21(Cip1) could be involved in the inhibition of proliferation and induction of differentiation in human NB cells induced by treatment with VPA or tributyrin or sodium butyrate. | Valproic Acid | cyclin dependent kinase inhibitor 1A | Homo sapiens |